Premier League leaders Arsenal host London rivals Tottenham Hotspur on Sunday as Manchester City seek to keep up the pressure on the Gunners.
Arsenal are expected to be without defensive lynchpin Gabriel Magalhaes during the North London derby at the Emirates Stadium.
Magalhaes has been at the heart of the near-impregnable Gunners back line that has conceded just five goals in 11 Premier League matches.
But reports suggest the Brazilian could be sidelined for weeks after suffering a thigh injury during Brazil’s 2-0 friendly win over Senegal at the Emirates Stadium last weekend.
Gabriel, who has formed a formidable central defensive partnership with William Saliba and is also a threat from set-pieces, is likely to be replaced by Piero Hincapie or Cristhian Mosquera.
The Gunners are four points clear of Manchester City after they drew 2-2 with Sunderland earlier this month, ending a streak of eight wins in all competitions with no goals conceded.
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Arsenal remain favourites to secure a first Premier League title since 2003/04 and have an eye-catching record against their London rivals – losing just once in the league at home to Tottenham since 1993.
But Spurs travel to the Emirates boasting the best away record in the league this season – with four wins and a draw from five games.
Pep Guardiola’s City could cut the Gunners’ lead at the top of the table to just one point, at least for 24 hours, if they beat Newcastle on Saturday.

Reigning champions Liverpool desperately need a win after five defeats in their last six Premier League matches, while Rob Edwards takes charge of his first match as Wolves manager.
Liverpool face Nottingham Forest, the only team who beat them at home last season, on Saturday with Arne Slot’s men desperate to put their recent woes behind them.
Below are the Premier League fixtures scheduled for the weekend:
Saturday
Burnley v Chelsea
Bournemouth v West Ham
Brighton v Brentford
Fulham v Sunderland
Liverpool v Nottingham Forest
Wolves v Crystal Palace
Newcastle v Manchester City
Sunday
Leeds v Aston Villa
Arsenal v Tottenham
Monday
Manchester United v Everton
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